Amanda Anisimova has pulled out of Rome due to a nagging left wrist injury that has prevented her from playing on clay this year.
The news was announced on Thursday by the tournament.
Anisimova, 11-6 on the season thus far, last played in Miami where she lost in the round of 16 to Belinda Bencic, 6-2, 6-2.
It has been a particularly turbulent spring for Anisimova, who parted ways with her longtime coach Hendrik Vleeshouwers in late March 2026 in late March.
Anisimova is on a trial basis with coach Sebastian Sachs, a former coach of Emma Raducanu and Belinda Bencic.
She has had to skip Charleston, Madrid and now Rome.
The two-time major finalist, aged 24 and ranked six, has been practicing. This tweet was posted on Wednesday, of Anisimova practicing with some taping on her left wrist in Rome.